Inflammation Reduction And Pain Relief
Reduces pain driven by inflammatory conditions associated with diseases like multiple sclerosis and rheumatoid arthritis.
Chemotherapy-Induced Nausea And Vomiting
Recent findings indicate that the cannabinoid system interacts with the 5-hydroxytryptaminergic system in the control of emesis. Both preclinical and human clinical research suggests that cannabinoid compounds may have promise in treating both nausea and vomiting in chemotherapy patients.
CBDa Appears To Be A Broader Function Form Of CBD That Is More Bioavailable.
- THCa and CBDa engage with the human endocannabinoid system by altering the efficiency of four primary functions: COX-1 Release, COX-2 Inhibition, TNF-Alpha Inhibition, Interleukin-10 Release.
- Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to inhibit both COX-1 and COX-2 activities. Inhibition of COX-2 accounts for the anti-inflammatory and analgesic effects of NSAIDs, whereas suppression of COX-1 can lead to many unwanted side effects.
- CBDa was also recently reported to demonstrate anticonvulsant and anti-nausea activity, possibly attributable to its serotonergic activity, in that CBDa demonstrates 100-fold greater affinity for the 5-HT1A receptor as compared to CBD.*
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